Stimulate glucose production, which may lead to increased blood sugar - though the scientific evidence is not conclusive.Īlthough recommendations can vary widely, most health organizations recommend an intake of at least 250–500 milligrams of combined EPA and DHA, or 2 servings of fatty fish per week ( 25, 26, 27, 28). Summary Taking high doses of omega-3 fatty acids can In fact, another analysis of 20 studies found that daily doses of up to 3.9 grams of EPA and 3.7 grams of DHA - the two main forms of omega-3 fatty acids - had no effect on blood sugar levels for individuals with type 2 diabetes ( 4). However, other research has turned up conflicting results, suggesting that only very high doses impact blood sugar. This is because large doses of omega-3s can stimulate the production of glucose, which can contribute to high levels of long-term blood sugar levels ( 3). One small study, for example, found that taking 8 grams of omega-3 fatty acids per day led to a 22% increase in blood sugar levels in people with type 2 diabetes over an eight-week period ( 2). Some research shows that supplementing with high amounts of omega-3 fatty acids could increase blood sugar levels in people with diabetes.
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